Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9959924 | 0.78 | TNNI3K (0.36) | — | |
| SCHEMBL9959605 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL25846913 | 0.77 | GABRR1 (0.39) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL9960250 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL10146748 | 0.69 | KDM4E (0.37) | TDP1 | |
| SCHEMBL11415123 | 0.68 | HIF1A (0.34) | CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL31631668 | 0.65 | GABRR1 (0.37) | HRH2HRH1HRH4HRH3TDP1 | |
| SCHEMBL11415127 | 0.64 | HIF1A (0.54) | HRH4CYP1A2HSD17B10 | |
| SCHEMBL5634287 | 0.64 | — | — | |
| SCHEMBL18229967 | 0.64 | GLP1R (0.41) | GLP1RHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085501-A1 | 8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG | PHARMINOX LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |