SCHEMBL10147111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10141182	0.92	HPGD (0.46)	HPGDALDH1A1TDP1CHRM2CHRM4
	SCHEMBL12232396	0.86	MAPT (0.42)	ALDH1A1TDP1MAPTNPSR1SMN1; SMN2
	SCHEMBL4909942	0.85	HPGD (0.47)	HPGDALDH1A1TP53TDP1NPSR1
	SCHEMBL4873791	0.85	HPGD (0.47)	HPGDALDH1A1TP53TDP1NPSR1
	SCHEMBL4873782	0.85	HPGD (0.47)	HPGDALDH1A1TP53TDP1NPSR1
	SCHEMBL4871362	0.78	MAPT (0.39)	TDP1MAPTNPSR1ATMGFER
	SCHEMBL4870454	0.78	MAPT (0.39)	TDP1MAPTNPSR1ATMGFER
	Hydrochloric Acid SCHEMBL4912494	0.76	MAPT (0.38)	MAPTNPSR1ATMGFER
	SCHEMBL23891619	0.75	MAPT (0.41)	ALDH1A1TDP1MAPTNPSR1SMN1; SMN2
	SCHEMBL22918217	0.75	HPGD (0.44)	HPGDALDH1A1TDP1CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.