Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351826 | 0.89 | CNR2 (0.36) | PTGS2PTGS1RAB9ACNR2NPSR1 | |
| SCHEMBL351741 | 0.79 | CNR2 (0.47) | RAB9ACNR2MAPTNPSR1KDM4E | |
| SCHEMBL1252448 | 0.77 | AR (0.32) | PTGS2PTGS1RAB9AKDM4E | |
| SCHEMBL10146112 | 0.77 | PIK3CG (0.38) | RAB9AMAPTKDM4E | |
| SCHEMBL10147493 | 0.76 | MAPK14 (0.33) | CNR2 | |
| SCHEMBL353351 | 0.74 | CNR2 (0.32) | CNR2KDM4E | |
| SCHEMBL13618555 | 0.73 | KDM4E (0.36) | KDM4E | |
| SCHEMBL351008 | 0.71 | CNR2 (0.39) | PTGS2PTGS1RAB9ACNR2KDM4E | |
| SCHEMBL351700 | 0.71 | CNR2 (0.36) | CNR2 | |
| SCHEMBL13618539 | 0.68 | MEN1 (0.38) | PTGS2CNR2MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |