Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351741 | 0.89 | CNR2 (0.47) | MEN1KMT2ACNR2NR1I2ALDH1A1 | |
| SCHEMBL351826 | 0.78 | CNR2 (0.36) | CNR2PTGS2ALDH1A1SMN1; SMN2CNR1 | |
| SCHEMBL350907 | 0.70 | CNR2 (0.51) | CNR2ALDH1A1CNR1MAPTKDM4E | |
| SCHEMBL10147508 | 0.68 | MAPT (0.37) | CNR2NOTUMMAPT | |
| SCHEMBL10147486 | 0.68 | PTGS2 (0.32) | CNR2PTGS2MAPTKDM4ENPSR1 | |
| SCHEMBL351891 | 0.67 | CNR2 (0.47) | MEN1KMT2ACNR2PTGS2ALDH1A1 | |
| SCHEMBL351577 | 0.67 | CNR2 (0.49) | MEN1KMT2ACNR2NR1I2PTGS2 | |
| SCHEMBL1250781 | 0.66 | CNR2 (0.39) | MEN1KMT2ACNR2NR1I2ALDH1A1 | |
| SCHEMBL1253112 | 0.66 | CNR2 (0.39) | CNR2NR1I2ALDH1A1NOTUMMAPT | |
| SCHEMBL350333 | 0.65 | CNR2 (0.47) | MEN1KMT2ACNR2NR1I2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |