Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 11/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123086 | 0.95 | GSTP1 (0.47) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL13212097 | 0.91 | ALDH1A1 (0.52) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL30378493 | 0.91 | ALDH1A1 (0.52) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL10123085 | 0.86 | ALDH1A1 (0.48) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL30378455 | 0.85 | MAPT (0.66) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL12387963 | 0.84 | MAPT (0.51) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL22434381 | 0.83 | GSTP1 (0.45) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL22434392 | 0.82 | GSTP1 (0.44) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL30378575 | 0.82 | ALDH1A1 (0.49) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL19878378 | 0.82 | ALDH1A1 (0.49) | MAPTMEN1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846168-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9372181-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2016-06-21 | — | — | US | disclosed |
| US-20140363824-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | MOLECULAR PROBES, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8785208-B2 | Fluorescent metal ion indicators with large stokes shifts | Life Technologies Corporation (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | Life Technologies Corporation (US) | 2012-01-12 | — | — | US | disclosed |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | Life Technologies Corporation (US) | 2010-08-05 | — | — | US | disclosed |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | Life Technologies Corporation (US) | 2010-08-05 | — | — | US | disclosed |
| US-20090029389-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | INVITROGEN CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
| US-20090029389-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | INVITROGEN CORPORATION (US) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009683-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MAPT 1199/4885MEN1 137/4885HTT 1710/4885 |
| US-20100196922-A1 | FLUORESCENT METAL ION INDICATORS WITH LARGE STOKES SHIFTS | SARAF, STIM1, ORAI1 | MAPT 1199/4885MEN1 137/4885HTT 1710/4885 |
| US-20160305964-A1 | Fluorescent Metal Ion Indicators with Large Stokes Shifts | SARAF, STIM1, ORAI1 | MAPT 1199/4885MEN1 137/4885HTT 1710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.