Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 2/20 | 0.37 |
| ▸ | PPIF | P30405 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657218 | 0.94 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1CYP19A1FFAR1MEN1 | |
| SCHEMBL10147694 | 0.94 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1CYP19A1FFAR1AKR1C3 | |
| SCHEMBL10147701 | 0.88 | CYP19A1 (0.43) | HSP90AA1HSP90AB1CYP19A1MEN1KMT2A | |
| SCHEMBL656734 | 0.87 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1CYP19A1FFAR1MEN1 | |
| SCHEMBL10147496 | 0.85 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1CYP19A1AKR1C3MAPT | |
| SCHEMBL10147697 | 0.85 | MAOB (0.43) | CYP19A1MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL7893314 | 0.83 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1MEN1KMT2AMAPT | |
| SCHEMBL657147 | 0.81 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1MEN1KMT2AMAPT | |
| SCHEMBL657321 | 0.81 | MAPT (0.46) | CYP19A1MEN1KMT2AMAPTPPIA | |
| SCHEMBL656618 | 0.80 | MAOB (0.45) | HSP90AA1CYP19A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993556-B2 | Resorcinol derivatives as HSP90 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-31 | — | — | US | disclosed |
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885HSP90AB1 1/4885CYP19A1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.