Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | PPIF | P30405 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657321 | 0.93 | MAPT (0.46) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10147697 | 0.91 | MAOB (0.43) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10147694 | 0.89 | HSP90AA1 (0.42) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10147699 | 0.88 | HSP90AA1 (0.50) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL656618 | 0.86 | MAOB (0.45) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10147497 | 0.83 | HSP90AA1 (0.52) | CYP19A1MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL656734 | 0.82 | HSP90AA1 (0.43) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL657218 | 0.81 | HSP90AA1 (0.51) | CYP19A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7895631 | 0.81 | HSP90AA1 (0.41) | MAPTMEN1KMT2APLA2G4BMCL1 | |
| SCHEMBL10147651 | 0.77 | CYP19A1 (0.53) | CYP19A1MAPTMEN1KMT2APPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993556-B2 | Resorcinol derivatives as HSP90 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-31 | — | — | US | disclosed |
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | CYP19A1 1582/4885MAPT 84/4885MEN1 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.