Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12778302 | 0.83 | GSK3B (0.36) | — | |
| SCHEMBL13122904 | 0.79 | ABL1 (0.35) | PARP1EGLN1 | |
| SCHEMBL10147755 | 0.73 | DYRK1A (0.42) | — | |
| SCHEMBL19364802 | 0.70 | TYMS (0.36) | — | |
| SCHEMBL503820 | 0.69 | EGLN1 (0.33) | PARP1EGLN1 | |
| SCHEMBL9652879 | 0.68 | EGFR (0.33) | — | |
| SCHEMBL17316253 | 0.64 | PARP1 (0.39) | PARP1EGLN1 | |
| SCHEMBL293195 | 0.64 | RIPK1 (0.51) | — | |
| SCHEMBL28522475 | 0.61 | PDE3B (0.36) | PARP1EGLN1 | |
| SCHEMBL16774902 | 0.61 | BRD4 (0.41) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120076755-A1 | Hepatitis C Virus Inhibitors | NSUN2, HCCS, HAVCR2 | PARP1 2356/4885EGLN1 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.