Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146096 | 0.80 | KDM4E (0.39) | KDM4EGRNSORT1KDM5B | |
| SCHEMBL13618719 | 0.79 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL18407334 | 0.70 | KDM4E (0.38) | KDM4EGRNSORT1KDM5B | |
| SCHEMBL18415303 | 0.69 | KDM5B (0.36) | KDM4EGRNSORT1KDM5B | |
| SCHEMBL10147819 | 0.68 | KDM4E (0.42) | KDM4EGRNSORT1 | |
| SCHEMBL10146074 | 0.68 | KDM4E (0.42) | KDM4EGRNSORT1 | |
| SCHEMBL13618716 | 0.68 | KDM4E (0.40) | KDM4EGRNSORT1 | |
| SCHEMBL10147794 | 0.68 | KDM4E (0.34) | KDM4EGRNSORT1KDM5B | |
| SCHEMBL10147796 | 0.67 | MAPT (0.37) | — | |
| SCHEMBL351577 | 0.67 | CNR2 (0.49) | KDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418207-A1 | Sulfone compounds which modulate the CB2 receptor | Boehringer Ingelheim International GmbH (DE) | 2012-02-15 | — | — | EP | disclosed |