Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146074 | 0.89 | KDM4E (0.42) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL10147819 | 0.80 | KDM4E (0.42) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL12747060 | 0.79 | KDM4E (0.41) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL13618719 | 0.77 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL10147799 | 0.75 | KDM4E (0.32) | KDM4EGRNSORT1 | |
| SCHEMBL10147538 | 0.75 | MAPK14 (0.40) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL351120 | 0.74 | CNR2 (0.51) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL10147492 | 0.72 | ALDH1A1 (0.34) | KDM4EGRNSORT1MAPK14MAPT | |
| SCHEMBL13618721 | 0.72 | KDM4E (0.36) | KDM4EGRNSORT1 | |
| SCHEMBL12824345 | 0.71 | MAPK14 (0.45) | KDM4EGRNSORT1MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |