SCHEMBL10147870

SCHEMBL10147870

CC(C)(C)OC(=O)N(c1cscn1)[S+]([O-])c1cc(F)c(F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN8A Q9UQD0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1094763 0.76 SCN8A (0.46) SCN8A
SCHEMBL20256826 0.73 SCN8A (0.54) SCN8A
SCHEMBL20256898 0.73 SCN8A (0.35) SCN8A
SCHEMBL20252570 0.72 SCN8A (0.55) SCN8A
SCHEMBL1109028 0.71 SCN8A (0.44) SCN8A
SCHEMBL19627627 0.71 SCN8A (0.46) SCN8A
SCHEMBL15464276 0.70 SCN8A (0.51) SCN8A
SCHEMBL326999 0.70 SCN8A (0.46) SCN8A
SCHEMBL16177622 0.70 SCN8A (0.47) SCN8A
SCHEMBL36151836 0.70 SCN8A (0.46) SCN8A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012004706-A2 CHEMICAL COMPOUNDS PFIZER LIMITED (GB) 2012-01-12 WO disclosed