Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094763 | 0.92 | SCN8A (0.46) | SCN8ASCN1A | |
| SCHEMBL29447344 | 0.90 | SCN8A (0.45) | SCN8A | |
| SCHEMBL19627718 | 0.90 | SCN8A (0.45) | SCN8A | |
| SCHEMBL36151836 | 0.88 | SCN8A (0.46) | SCN8ASCN1A | |
| SCHEMBL29668979 | 0.88 | SCN8A (0.47) | SCN8A | |
| SCHEMBL21789095 | 0.88 | SCN8A (0.44) | SCN8A | |
| SCHEMBL16177622 | 0.88 | SCN8A (0.47) | SCN8A | |
| SCHEMBL326999 | 0.88 | SCN8A (0.46) | SCN8ASCN1A | |
| SCHEMBL20252570 | 0.83 | SCN8A (0.55) | SCN8ASCN1A | |
| SCHEMBL20574121 | 0.83 | SCN8A (0.48) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153814-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2012-04-10 | — | — | US | disclosed |
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited Icagen, Inc. | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197655-A1 | SULFONAMIDE DERIVATIVES | SULT2A1, SULT1A1, TPST2 | SCN8A 32/4885SCN1A 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.