Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711390 | 0.83 | TLR7 (0.55) | TLR7 | |
| SCHEMBL6977161 | 0.83 | TLR7 (0.55) | TLR7 | |
| SCHEMBL10148001 | 0.80 | TLR7 (0.47) | TLR7 | |
| SCHEMBL6976058 | 0.80 | TLR7 (0.54) | TLR7 | |
| SCHEMBL12111830 | 0.73 | AHCY (0.33) | TLR7 | |
| SCHEMBL10147992 | 0.70 | TLR7 (0.53) | TLR7 | |
| SCHEMBL10147996 | 0.70 | TLR7 (0.51) | TLR7 | |
| SCHEMBL15295594 | 0.70 | TLR7 (0.59) | TLR7 | |
| SCHEMBL15292922 | 0.70 | TLR7 (0.59) | TLR7 | |
| SCHEMBL6973037 | 0.70 | TLR7 (0.56) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |