Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12628920 | 0.90 | TSHR (0.49) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL15025739 | 0.90 | HPGD (0.57) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL16329238 | 0.90 | SMN1; SMN2 (0.48) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24686268 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24686941 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24686272 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24686927 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24687404 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL19380534 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL | |
| SCHEMBL24687409 | 0.88 | HPGD (0.63) | HPGDHTTSMN1; SMN2TSHRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106131-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090012241-A1 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-01-08 | — | — | US | disclosed |
| US-7432331-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432330-B2 | Hydrolytically stable maleimide-terminated polymers | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |