Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 16/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147725 | 1.00 | ALDH1A1 (0.43) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL6972453 | 0.86 | ALDH1A1 (0.45) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL12111919 | 0.85 | ALDH1A1 (0.44) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL12112020 | 0.85 | ALDH1A1 (0.44) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL14724959 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL4284935 | 0.83 | ALDH1A1 (0.43) | ALDH1A1ABCB1NPC1 | |
| SCHEMBL16576324 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL27087661 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL20557502 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ABCB1NPC1TSHR | |
| SCHEMBL29324933 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ABCB1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097718-B2 | 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof | ANADYS PHARMACEUTICALS, INC. (US) | 2012-01-17 | — | — | US | disclosed |