Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | RORA | P35398 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | RORB | Q92753 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127794 | 0.93 | POLB (0.47) | POLBPGRRORARORCRORB | |
| SCHEMBL10127725 | 0.93 | POLB (0.47) | POLBPGRRORARORCRORB | |
| SCHEMBL10127813 | 0.92 | POLB (0.45) | POLBPGRRORARORCRORB | |
| SCHEMBL10127736 | 0.92 | POLB (0.45) | POLBPGRRORARORCRORB | |
| SCHEMBL10127860 | 0.86 | POLB (0.43) | POLBMAPTALDH1A1MAPK1NPSR1 | |
| SCHEMBL10127777 | 0.86 | POLB (0.43) | POLBMAPTALDH1A1MAPK1NPSR1 | |
| SCHEMBL10127801 | 0.85 | POLB (0.45) | POLBPGRRORARORCRORB | |
| SCHEMBL10127726 | 0.85 | POLB (0.45) | POLBPGRRORARORCRORB | |
| SCHEMBL10127733 | 0.83 | HSD11B1 (0.44) | POLBPGRRORARORCRORB | |
| SCHEMBL10127803 | 0.83 | HSD11B1 (0.44) | POLBPGRRORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017842-A1 | TRIAZOLE DERIVATIVE, HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-02-09 | — | — | WO | disclosed |