SCHEMBL1014917

SCHEMBL1014917

N#Cc1c(Cl)nc(Cl)nc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
MAPK1 P28482 3/20 0.43
NSD2 O96028 1/20 0.43
KDM4E B2RXH2 2/20 0.42
KMT2A Q03164 7/20 0.41
MEN1 O00255 5/20 0.41
MAPT P10636 3/20 0.41
TP53 P04637 2/20 0.41
HPGD P15428 2/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.39
HTT P42858 6/20 0.38
GLA P06280 2/20 0.38
L3MBTL1 Q9Y468 5/20 0.37
GAA P10253 2/20 0.37
LMNA P02545 1/20 0.37
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15571327 0.83 ALDH1A1 (0.59) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL11826738 0.83 KDM4E (0.48) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL17458364 0.78 ALDH1A1 (0.54) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL11830021 0.78 CYP1A2 (0.47) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL11171320 0.78 ALDH1A1 (0.40) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL9640969 0.78 KMT2A (0.53) ALDH1A1MAPK1KDM4EKMT2AMEN1
SCHEMBL8072518 0.77 KMT2A (0.55) ALDH1A1MAPK1NSD2KDM4EKMT2A
SCHEMBL32688195 0.73 KMT2A (0.63) ALDH1A1KDM4EKMT2AMEN1HPGD
SCHEMBL11175610 0.73 RXFP1 (0.43) ALDH1A1MAPK1NSD2KDM4EMAPT
SCHEMBL13405793 0.72 KMT2A (0.40) ALDH1A1MAPK1NSD2KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504610-A Multi-azido heterocyclic energetic compound and preparation method and application thereof 南京理工大学 2025-02-25 CN claimed
CN-110106700-A A kind of cellulose base fiber fabric anti-pilling finishing liquid and method for sorting 苏州大学 2019-08-09 CN claimed
EP-0365486-B1 Fibre-reactive azo dyes SANDOZ AG (CH) 1995-07-19 EP claimed
WO-1995012585-A1 TEXTILE TREATMENT UNIVERSITY OF LEEDS (GB) 1995-05-11 WO claimed
EP-0365486-A2 Fibre-reactive azo dyes SANDOZ AG (CH) 1990-04-25 EP claimed
EP-0225730-A2 Reactive Dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-06-16 EP claimed
JP-2242861-A None JP disclosed
JP-6220348-A None JP disclosed
CN-119504610-B Multi-azido heterocyclic energetic compound and preparation method and application thereof 南京理工大学 2026-04-21 CN disclosed
EP-3727380-B1 PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA MERCK SHARP & DOHME LLC (US) 2025-09-24 EP disclosed
US-20250276981-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. 2025-09-04 US disclosed
EP-4536650-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 EP disclosed
CN-119504610-A Multi-azido heterocyclic energetic compound and preparation method and application thereof 南京理工大学 2025-02-25 CN disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4065446-A Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3975384-A ANTITHROMBOTICS BOEHRINGER INGELHEIM GMBH (DT) 1976-08-17 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276981-A1 TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS BCL6, BCL6B, BCOR ALDH1A1 512/4885MAPK1 4213/4885NSD2 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.