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SCHEMBL10149217

SCHEMBL10149217

O=S(=O)(c1ccc(F)cc1)N1Cc2ccccc2N(Cc2cnc[nH]2)C(CCc2ccccc2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CYP2C9 P11712 2/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10165695 0.92 CYP2C9 (0.84) CYP2C9
SCHEMBL10149949 0.86 CYP2C9 (0.75) CYP2C9
SCHEMBL10149661 0.86 CYP2C9 (0.72) CYP2C9
SCHEMBL10149646 0.84 CYP2C9 (0.70) CYP2C9
SCHEMBL20644349 0.83 CYP2C9 (0.59) CYP2C9
SCHEMBL10149148 0.82 CYP2C9 (0.69) CYP2C9
SCHEMBL14071249 0.82 CYP2C9 (0.67) CYP2C9
SCHEMBL10149140 0.82 CYP2C9 (0.59) CYP2C9
SCHEMBL10165701 0.81 CYP2C9 (0.70) CYP2C9
SCHEMBL10165691 0.75 CYP2C9 (0.61) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2422788-A2 Benzodiazepines and compositions and uses thereof THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2012-02-29 — — EP disclosed
EP-2216073-A1 Methods and compositions for treating diseases and conditions associated with mitochondrial function THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2010-08-11 — — EP disclosed
WO-2008116156-A2 METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS ASSOCIATED WITH MITOCHONDRIAL FUNCTION THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2008-09-25 — — WO disclosed
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