Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10149217 | 0.92 | CYP2C9 (0.81) | CYP2C9 | |
| SCHEMBL10149949 | 0.88 | CYP2C9 (0.75) | CYP2C9 | |
| SCHEMBL10149661 | 0.86 | CYP2C9 (0.72) | CYP2C9 | |
| SCHEMBL10149646 | 0.84 | CYP2C9 (0.70) | CYP2C9 | |
| SCHEMBL10165701 | 0.84 | CYP2C9 (0.70) | CYP2C9 | |
| SCHEMBL10165691 | 0.83 | CYP2C9 (0.61) | CYP2C9 | |
| SCHEMBL10149148 | 0.82 | CYP2C9 (0.69) | CYP2C9 | |
| SCHEMBL14071249 | 0.82 | CYP2C9 (0.67) | CYP2C9 | |
| SCHEMBL20644365 | 0.78 | CYP2C9 (0.81) | CYP2C9 | |
| SCHEMBL10149140 | 0.77 | CYP2C9 (0.59) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077805-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-03-29 | — | — | US | disclosed |
| US-7994313-B2 | Unsolvated benzodiazepine compositions and methods | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-08-09 | — | — | US | disclosed |
| US-20090275099-A1 | Methods and compositions for treating diseases and conditions associated with mitochondrial function | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090253686-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-10-08 | — | — | US | disclosed |
| US-20080293700-A1 | Compositions and Methods Relating to Novel Compounds and Targets Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2008-11-27 | — | — | US | disclosed |
| US-20070043033-A1 | Unsolvated benzodiazepine compositions and methods | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293700-A1 | Compositions and Methods Relating to Novel Compounds and Targets Thereof | BAX, BAD, GABRB3 | CYP2C9 2812/4885 |
| US-20090275099-A1 | Methods and compositions for treating diseases and conditions associated with mitochondrial function | ATP5F1A, ATP5MF, MT-ATP6 | CYP2C9 3741/4885 |
| US-20120077805-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | GABRA5, GABRA3, GABRA6 | CYP2C9 84/4885 |
| US-20070043033-A1 | Unsolvated benzodiazepine compositions and methods | GABRA5, GABRA3, GABRA6 | CYP2C9 84/4885 |
| US-20090253686-A1 | UNSOLVATED BENZODIAZEPINE COMPOSITIONS AND METHODS | GABRA5, GABRA3, GABRA6 | CYP2C9 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.