Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705920 | 0.87 | EGFR (0.51) | AKR1C3AKR1B10AKR1B1ALDH1A1NPSR1 | |
| SCHEMBL2705918 | 0.87 | EGFR (0.51) | AKR1C3AKR1B10AKR1B1ALDH1A1NPSR1 | |
| SCHEMBL10898081 | 0.84 | EGFR (0.56) | AKR1C3AKR1B10AKR1B1ALDH1A1NPSR1 | |
| SCHEMBL10898075 | 0.84 | EGFR (0.56) | AKR1C3AKR1B10AKR1B1ALDH1A1NPSR1 | |
| SCHEMBL16832048 | 0.83 | TTR (0.56) | AKR1C3AKR1B1ALDH1A1NPSR1KDM4E | |
| SCHEMBL16832047 | 0.83 | TTR (0.56) | AKR1C3AKR1B1ALDH1A1NPSR1KDM4E | |
| SCHEMBL12555874 | 0.81 | AKR1C3 (0.66) | AKR1C3AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL2601403 | 0.81 | AKR1C3 (0.66) | AKR1C3AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL29395741 | 0.81 | AKR1C3 (0.66) | AKR1C3AKR1B10AKR1B1ALDH1A1KDM4E | |
| SCHEMBL111230 | 0.80 | KDM4E (0.58) | AKR1C3AKR1B10AKR1B1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160288090-A1 | MOLECULARLY IMPRINTED POLYMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-10-06 | — | — | US | disclosed |
| US-8466291-B2 | 1,5-dideoxy-1,5-imino-D-glucitol compounds | ACADEMIA SINICA (TW) | 2013-06-18 | — | — | US | disclosed |
| US-20120052757-A1 | MOLECULARLY IMPRINTED POLYMERS | MONASH UNIVERSITY (AU) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160288090-A1 | MOLECULARLY IMPRINTED POLYMERS | IPMK, MPI, PIM3 | AKR1C3 1493/4885AKR1B10 1477/4885AKR1B1 1341/4885 |
| US-20120052757-A1 | MOLECULARLY IMPRINTED POLYMERS | IPMK, MPI, PIM3 | AKR1C3 1493/4885AKR1B10 1477/4885AKR1B1 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.