Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA3 | P07451 | 3/20 | 0.58 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | CA6 | P23280 | 3/20 | 0.58 |
| ▸ | CA5A | P35218 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584596 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL27875555 | 0.85 | HSD17B10 (0.56) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL5859843 | 0.85 | AKR1C3 (0.64) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL14472602 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL471934 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL471935 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL5859847 | 0.85 | AKR1C3 (0.64) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL14926717 | 0.84 | IAPP (0.61) | KDM4EALDH1A1POLBTDP1LMNA | |
| SCHEMBL7003926 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MAPK1CA12 | |
| SCHEMBL7003924 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268614-B1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | SHOWA DENKO KK (JP) | 2013-05-15 | — | — | EP | claimed |
| US-8258340-B2 | Method for producing β-mercapto carboxylic acids | SHOWA DENKO K.K. (JP) | 2012-09-04 | — | — | US | claimed |
| US-20110015436-A1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | SHOWA DENKO K.K. (JP) | 2011-01-20 | — | — | US | claimed |
| EP-2268614-A1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | Showa Denko K.K. (JP) | 2011-01-05 | — | — | EP | claimed |
| WO-2009113711-A1 | METHOD FOR PRODUCING -MERCAPTO CARBOXYLIC ACIDS | SHOWA DENKO K.K. (JP) | 2009-09-17 | — | — | WO | claimed |
| US-3943137-A | ANTITUMOR | UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1976-03-09 | — | — | US | claimed |
| JP-4149165-A | — | — | None | — | — | JP | disclosed |
| US-20230151011-A1 | PURINE COMPOUNDS FOR TREATING DISORDERS | MARVEL BIOTECHNOLOGY (CA) | 2023-05-18 | — | — | US | disclosed |
| WO-2020219714-A1 | NOVEL SMALL MOLECULES THAT BIND AND/OR MODULATE DIFFERENTFORMS OF TAU OLIGOMERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-10-29 | — | — | WO | disclosed |
| US-10233183-B1 | 13-hydroxysparteine cinnamic acid derivatives with anti-tumor activities and a method of preparing the same | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-03-19 | — | — | US | disclosed |
| US-9951087-B2 | Fused ring analogues of anti-fibrotic agents | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2018-04-24 | — | — | US | disclosed |
| US-9802898-B2 | Phenyl and tertbutylacetic acid substituted pyridinones having anti-HIV effects | VIIV HEALTHCARE UK LIMITED (GB) | 2017-10-31 | — | — | US | disclosed |
| US-20170217890-A1 | PHENYL AND TERTBUTYLACETIC ACID SUBSTITUTED PYRIDINONES HAVING ANTI-HIV EFFECTS | VIIV HEALTHCARE UK LIMITED (GB) | 2017-08-03 | — | — | US | disclosed |
| EP-0565377-A1 | Therapeutic agents for use in the treatment of parkinson's disease | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| JP-H04149165-A | PRODUCTION OF AMINO BENZOIC ACID DERIVATIVE | MARUKO SEIYAKU KK | 1992-05-22 | — | — | JP | disclosed |
| US-RE32944-E | Aromatic carboxylic amide derivatives | Kissei Yakuhin Kogyo Kabushiki (JP) | 1989-06-06 | — | — | US | disclosed |
| US-4070484-A | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |
| US-4026896-A | ANTIALLERGENS | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3943137-A | ANTITUMOR | UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3940422-A | ANTIALLERGEN | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233183-B1 | 13-hydroxysparteine cinnamic acid derivatives with anti-tumor activities and a method of preparing the same | CYP51A1, CYP46A1, HSD17B13 | KDM4E 4042/4885ALDH1A1 175/4885HSD17B10 62/4885 |
| US-20170217890-A1 | PHENYL AND TERTBUTYLACETIC ACID SUBSTITUTED PYRIDINONES HAVING ANTI-HIV EFFECTS | TERT, CD4, TYMP | KDM4E 1927/4885ALDH1A1 271/4885HSD17B10 1073/4885 |
| US-20230151011-A1 | PURINE COMPOUNDS FOR TREATING DISORDERS | ADORA2A, ADORA1, ADORA3 | KDM4E 3156/4885ALDH1A1 590/4885HSD17B10 3692/4885 |
| US-20110015436-A1 | METHOD FOR PRODUCING BETA-MERCAPTO CARBOXYLIC ACIDS | CBS, ALDH7A1, CBR1 | KDM4E 3784/4885ALDH1A1 8/4885HSD17B10 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.