Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123599 | 0.74 | TSHR (0.37) | MEN1KMT2AKDM4EALDH1A1GABRA1 | |
| SCHEMBL23116419 | 0.72 | GABRA1 (0.33) | KDM4EALDH1A1CASP1HSD17B10GABRA1 | |
| SCHEMBL39547 | 0.68 | — | — | |
| SCHEMBL29565534 | 0.68 | — | — | |
| Bromide SCHEMBL28472529 | 0.66 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1ALOX15CASP1 | |
| Water SCHEMBL27919614 | 0.66 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1ALOX15CASP1 | |
| Ammonia Solution, Strong SCHEMBL27637031 | 0.66 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1ALOX15CASP1 | |
| Water SCHEMBL17512841 | 0.66 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1ALOX15CASP1 | |
| Iodide SCHEMBL29238182 | 0.66 | CYP3A4 (0.47) | MAPTKDM4EALDH1A1ALOX15CASP1 | |
| Hydrochloric Acid SCHEMBL1585890 | 0.66 | CYP3A4 (0.48) | MAPTKDM4EALDH1A1ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415771-A1 | INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |