⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158833 | 0.81 | KMT2A (0.35) | — | |
| SCHEMBL13020467 | 0.60 | — | — | |
| SCHEMBL16436141 | 0.57 | ALB (0.32) | — | |
| SCHEMBL15369632 | 0.57 | ALB (0.46) | — | |
| SCHEMBL18720669 | 0.56 | RXFP1 (0.41) | — | |
| SCHEMBL17232084 | 0.55 | — | — | |
| SCHEMBL16000608 | 0.52 | — | — | |
| SCHEMBL14768699 | 0.52 | PDE4D (0.46) | — | |
| SCHEMBL10324251 | 0.52 | PDE4D (0.46) | — | |
| SCHEMBL17232080 | 0.52 | POLA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170002037-A1 | CYCLIC NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. | 2017-01-05 | — | — | US | disclosed |
| US-8772474-B2 | Cyclic nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120165286-A1 | CYCLIC NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-06-28 | — | — | US | disclosed |