Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720809 | 0.89 | PPARG (0.64) | PPARGPPARAALDH1A1TBXAS1MEN1 | |
| SCHEMBL2720808 | 0.89 | PPARG (0.64) | PPARGPPARAALDH1A1TBXAS1MEN1 | |
| SCHEMBL13994556 | 0.84 | PPARG (0.50) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL13994554 | 0.84 | PPARG (0.50) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL4680580 | 0.83 | PPARG (0.63) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL4680583 | 0.83 | PPARG (0.63) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719672 | 0.82 | PPARG (0.59) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719676 | 0.82 | PPARG (0.59) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719648 | 0.81 | PPARG (0.58) | PPARGPPARAALDH1A1MEN1LMNA | |
| SCHEMBL2719645 | 0.81 | PPARG (0.58) | PPARGPPARAALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1647546-B1 | NOVEL HETEROARYL DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-05-02 | — | — | EP | disclosed |