SCHEMBL101519

SCHEMBL101519

O=C(O)C(Cl)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.46
PPARA Q07869 14/20 0.46
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
CYP2C19 P33261 1/20 0.46
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
LDHA P00338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28131536 0.98 PPARG (0.45) PPARGPPARACYP1A2GAACYP2C9
Phosphine SCHEMBL28858272 0.98 PPARG (0.45) PPARGPPARACYP1A2GAACYP2C9
Dimethylamine SCHEMBL27771570 0.92 MTNR1A (0.45) PPARGPPARACYP1A2GAACYP2C9
SCHEMBL11408417 0.85 PPARG (0.42) PPARGPPARAMEN1ALDH1A1KMT2A
SCHEMBL10333646 0.84 MEN1 (0.42) PPARGPPARACYP1A2GAACYP2C9
SCHEMBL11212800 0.84 MEN1 (0.42) PPARGPPARACYP1A2GAACYP2C9
SCHEMBL367795 0.83 PPARG (0.56) PPARGPPARA
SCHEMBL6275712 0.83 MTNR1A (0.47) PPARGPPARACYP1A2GAACYP2C9
SCHEMBL7408531 0.83 PARP10 (0.42) PPARGPPARACYP1A2GAACYP2C9
SCHEMBL10763803 0.81 MEN1 (0.40) PPARGPPARACYP1A2GAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2025-09-23 US claimed
CN-113735792-B Preparation method of meglumine cloxazoate and intermediate thereof 上海新礼泰药业有限公司 2024-10-18 CN claimed
CN-118330212-A 4-Chlorophenoxyacetic acid colloidal gold detection test strip and application thereof 闽南师范大学 2024-07-12 CN claimed
EP-4320094-A1 NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF Cosmas Therapeutics Development Inc. (CA) 2024-02-14 EP claimed
US-11849693-B2 Maize varieties ‘164-005>1’ and ‘164-005>2’ FBN Inputs, LLC (US) 2023-12-26 US claimed
US-11839190-B2 Maize variety ‘166-048’ FBN Inputs, LLC (US) 2023-12-12 US claimed
CN-116940236-A Composition containing benzylamine acaricide and application thereof 山东康乔生物科技有限公司 2023-10-24 CN claimed
CN-115928110-A Hydrogenation dechlorination method of high-concentration chlorinated aromatic compound 浙江工业大学 2023-04-07 CN claimed
CN-111988993-B Emulsifiable concentrates 陶氏环球技术有限责任公司 2022-12-20 CN claimed
CN-112047837-B 4-chlorophenoxyacetic acid hapten, artificial antigen and application thereof in immunodetection 广东达元绿洲食品安全科技股份有限公司 2022-11-08 CN claimed
EP-0672162-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF $i(TAXUS) SPECIES PHYTON CATALYTIC, INC. (US) 1995-09-20 EP claimed
EP-0283369-B1 Use of Metformin in the preparation of medicaments LIPHA (FR) 1993-12-08 EP claimed
WO-1993017121-A1 ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES PHYTON CATALYTIC, INC. (US) 1993-09-02 WO claimed
EP-0487623-A1 DERIVATIVES OF 5-AMINO-1,2,3,4 TETRAHYDRO-ACRIDINE AND APPLICATIONS AS DRUGS SYNTHESES ET RECHERCHES (FR) 1992-06-03 EP claimed
WO-1991002725-A1 DERIVATIVES OF 5-AMINO-1,2,3,4 TETRAHYDRO-ACRIDINE AND APPLICATIONS AS DRUGS SYNTHESES ET RECHERCHES (FR) 1991-06-07 WO claimed
EP-0283369-A2 Use of Metformin in the preparation of medicaments LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1988-09-21 EP claimed
US-4637830-A ALKANOIC ESTERS OF IOXYNIL AND BROMOXYNIC WITH SALTS OF CHLOROBENZOIC ACID OR CHLOROPHENOXYALKANOIC ACID CIBA-GEIGY CORPORATION (US) 1987-01-20 US claimed
EP-0079668-B1 PESTICIDE PRODUCT AND USE AND MANUFACTURE THEREOF SIERRA CHEMICAL COMPANY (US) 1986-02-26 EP claimed
EP-0079668-A1 Pesticide product and use and manufacture thereof SIERRA CHEMICAL COMPANY (US) 1983-05-25 EP claimed
WO-1983000799-A1 SLOW RELEASE PESTICIDE AND COMPOSITE GRANULES AND METHOD FOR MAKING THE SAME SIERRA CHEM (US) 1983-03-17 WO claimed