SCHEMBL101520

SCHEMBL101520

O=C(O)COc1ccccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 3/20 0.68
KMT2A Q03164 3/20 0.63
TDP1 Q9NUW8 4/20 0.62
POLB P06746 4/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
GLA P06280 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
RAB9A P51151 2/20 0.61
MEN1 O00255 2/20 0.58
HPGD P15428 2/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
MAPT P10636 1/20 0.57
RECQL P46063 1/20 0.57
RXRA P19793 1/20 0.56
RXRB P28702 1/20 0.56
TSHR P16473 1/20 0.56
TP53 P04637 1/20 0.56
HTT P42858 1/20 0.56
ALOX15 P16050 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28131537 0.98 PTGDR2 (0.66) PTGDR2KMT2ATDP1POLBSMN1; SMN2
SCHEMBL28178693 0.98 PTGDR2 (0.66) PTGDR2KMT2ATDP1POLBSMN1; SMN2
2,4-Dichlorophenoxyacetic Acid SCHEMBL30969691 0.88 TDP1 (0.84) PTGDR2KMT2ATDP1SMN1; SMN2MEN1
SCHEMBL12147210 0.85 PTGDR2 (0.60) PTGDR2KMT2ATDP1POLBSMN1; SMN2
SCHEMBL340762 0.85 L3MBTL1 (0.80) PTGDR2KMT2ATDP1POLBSMN1; SMN2
SCHEMBL29682135 0.85 L3MBTL1 (0.80) PTGDR2KMT2ATDP1POLBSMN1; SMN2
SCHEMBL692136 0.85 KMT2A (0.65) PTGDR2KMT2ATDP1POLBSMN1; SMN2
SCHEMBL3254718 0.84 MEN1 (0.58) KMT2ATDP1POLBSMN1; SMN2L3MBTL1
SCHEMBL28030039 0.83 L3MBTL1 (0.53) PTGDR2KMT2ATDP1POLBSMN1; SMN2
Water SCHEMBL28856010 0.83 KMT2A (0.62) PTGDR2KMT2ATDP1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2398 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2025-09-23 US claimed
CN-119735715-A Cross-linked amino chitosan and preparation and application thereof 中国科学院烟台海岸带研究所 2025-04-01 CN claimed
CN-119736270-A L-aspartate aminotransferase mutant and application thereof 合肥工业大学 2025-04-01 CN claimed
CN-113735792-B Preparation method of meglumine cloxazoate and intermediate thereof 上海新礼泰药业有限公司 2024-10-18 CN claimed
CN-118330212-A 4-Chlorophenoxyacetic acid colloidal gold detection test strip and application thereof 闽南师范大学 2024-07-12 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117946305-B Phenoxyacetic acid resin and preparation method thereof, and method for removing calcium and magnesium from salt lake brine 江苏海普功能材料有限公司 2024-06-07 CN claimed
CN-117946305-A Phenoxyacetic acid resin and preparation method thereof, and method for removing calcium and magnesium from salt lake brine 江苏海普功能材料有限公司 2024-04-30 CN claimed
EP-4320094-A1 NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF Cosmas Therapeutics Development Inc. (CA) 2024-02-14 EP claimed
US-11849693-B2 Maize varieties ‘164-005>1’ and ‘164-005>2’ FBN Inputs, LLC (US) 2023-12-26 US claimed
EP-0487623-A1 DERIVATIVES OF 5-AMINO-1,2,3,4 TETRAHYDRO-ACRIDINE AND APPLICATIONS AS DRUGS SYNTHESES ET RECHERCHES (FR) 1992-06-03 EP claimed
WO-1991002725-A1 DERIVATIVES OF 5-AMINO-1,2,3,4 TETRAHYDRO-ACRIDINE AND APPLICATIONS AS DRUGS SYNTHESES ET RECHERCHES (FR) 1991-06-07 WO claimed
US-4868092-A SENSITIVE TO VISIBLE LIGHT, XANTHENE DYE INITIATOR NIPPON PAINT CO., LTD. (JP) 1989-09-19 US claimed
EP-0299973-A1 ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. UPJOHN CO (US) 1989-01-25 EP claimed
EP-0283369-A2 Use of Metformin in the preparation of medicaments LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1988-09-21 EP claimed
WO-1987006133-A1 ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-10-22 WO claimed
EP-0079668-B1 PESTICIDE PRODUCT AND USE AND MANUFACTURE THEREOF SIERRA CHEMICAL COMPANY (US) 1986-02-26 EP claimed
EP-0021177-B1 MAYTANSINOIDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1984-02-08 EP claimed
EP-0079668-A1 Pesticide product and use and manufacture thereof SIERRA CHEMICAL COMPANY (US) 1983-05-25 EP claimed
WO-1983000799-A1 SLOW RELEASE PESTICIDE AND COMPOSITE GRANULES AND METHOD FOR MAKING THE SAME SIERRA CHEM (US) 1983-03-17 WO claimed