Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.40 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390337 | 0.98 | KCNH2 (0.41) | KCNH2SCN5ACACNA1CTAAR1GABRA1 | |
| SCHEMBL30806201 | 0.88 | KCNH2 (0.42) | KCNH2SCN5ACACNA1CTAAR1GABRA1 | |
| SCHEMBL10390338 | 0.87 | SMN1; SMN2 (0.42) | KCNH2SCN5ACACNA1CCXCL8CYP3A4 | |
| SCHEMBL114811 | 0.85 | SCN5A (0.48) | KCNH2SCN5ACACNA1CGABRA1GABRB2 | |
| SCHEMBL10390197 | 0.84 | TSHR (0.37) | KCNH2SCN5ACACNA1CCXCL8CYP3A4 | |
| SCHEMBL11660113 | 0.82 | KCNH2 (0.49) | KCNH2SCN5ACACNA1CTAAR1GABRA1 | |
| SCHEMBL11242607 | 0.80 | CYP1A2 (0.48) | TAAR1PTGS2PTGS1AKR1B10UGT1A9 | |
| SCHEMBL998947 | 0.78 | PTGS2 (0.49) | KCNH2SCN5ACACNA1CGABRA1GABRB2 | |
| SCHEMBL29418253 | 0.78 | PTGS2 (0.49) | KCNH2SCN5ACACNA1CGABRA1GABRB2 | |
| SCHEMBL29440296 | 0.74 | KCNH2 (0.35) | KCNH2SCN5ACACNA1CGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978791-A | CROSSLINKING OR CHAIN EXTENSION AGENTS FOR POLYURETHANES OR EPOXY RESINS | LONZA LTD. (CH) | 1990-12-18 | — | — | US | claimed |
| EP-0171588-A1 | Chain-lengthening or cross-linking agent | LONZA AG (CH) | 1986-02-19 | — | — | EP | claimed |
| EP-3583150-B1 | GLYCIDYL AMINE EPOXY RESINS BASED ON AMES NEGATIVE AMINES | ADITYA BIRLA CHEMICALS THAILAND LTD (TH) | 2023-06-07 | — | — | EP | disclosed |
| WO-2015071074-A1 | TWO-COMPONENT ADHESIVE | NOLAX AG (CH) | 2015-05-21 | — | — | WO | disclosed |
| EP-2426157-A1 | Diamine compositions and use thereof | Lonza Ltd. (CH) | 2012-03-07 | — | — | EP | disclosed |
| US-4978791-A | CROSSLINKING OR CHAIN EXTENSION AGENTS FOR POLYURETHANES OR EPOXY RESINS | LONZA LTD. (CH) | 1990-12-18 | — | — | US | disclosed |
| US-4978791-A | CROSSLINKING OR CHAIN EXTENSION AGENTS FOR POLYURETHANES OR EPOXY RESINS | LONZA LTD. (CH) | 1990-12-18 | — | — | US | disclosed |
| EP-0171588-B1 | CHAIN-LENGTHENING OR CROSS-LINKING AGENT | LONZA AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0171588-A1 | Chain-lengthening or cross-linking agent | LONZA AG (CH) | 1986-02-19 | — | — | EP | disclosed |