SCHEMBL10153153

SCHEMBL10153153

COc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3ccccc3-4)c3cccc(OC)c23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.42
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
CYP1A1 P04798 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP1B1 Q16678 2/20 0.36
HSP90AA1 P07900 1/20 0.36
PGR P06401 1/20 0.36
BACE1 P56817 1/20 0.36
ABL1 P00519 1/20 0.35
ABCB1 P08183 1/20 0.35
BCR P11274 1/20 0.35
ACACA Q13085 1/20 0.35
ACHE P22303 1/20 0.35
SYK P43405 2/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153199 0.92 PDK2 (0.43) PDK2ALDH1A1MAPTHSP90AA1L3MBTL1
SCHEMBL14600442 0.91 PDK2 (0.43) PDK2ALDH1A1MAPTL3MBTL1
SCHEMBL10153818 0.89 PDK2 (0.50) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153227 0.88 PDK2 (0.49) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153835 0.88 PDK2 (0.49) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153443 0.88 PDK2 (0.52) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153348 0.88 PDK2 (0.52) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153548 0.88 PDK2 (0.52) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL14600432 0.88 PDK2 (0.52) PDK2KDM4EALDH1A1LMNAMAPT
SCHEMBL10153200 0.87 PDK2 (0.37) PDK2KDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed