SCHEMBL10153200

SCHEMBL10153200

COc1cccc2c(-c3ccc4c(c3)C(C)(C)c3cc(-c5ccc6c(c5)C(C)(C)c5cc(-c7c8ccccc8c(-c8ccc(-c9ccccc9)cc8)c8c(OC)cccc78)ccc5-6)ccc3-4)c3ccccc3c(-c3ccc(-c4ccccc4)cc3)c12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.37
ACACA Q13085 1/20 0.36
HPGD P15428 3/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
AR P10275 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PDE10A Q9Y233 1/20 0.34
STK10 O94804 3/20 0.34
SLK Q9H2G2 3/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153896 0.98 PDK2 (0.37) PDK2ACACAHPGDLMNASMN1; SMN2
SCHEMBL14600442 0.89 PDK2 (0.43) PDK2SMN1; SMN2ALDH1A1MAPTSTK10
SCHEMBL10153199 0.88 PDK2 (0.43) PDK2SMN1; SMN2ALDH1A1MAPTMEN1
SCHEMBL10153153 0.87 PDK2 (0.42) PDK2ACACAHPGDLMNAKDM4E
SCHEMBL14600487 0.83 ACACA (0.44) PDK2ACACAHPGDLMNASMN1; SMN2
SCHEMBL9934902 0.81 PPARG (0.42) PDK2ACACAALDH1A1MAPTPDE10A
SCHEMBL14600414 0.81 PDK2 (0.51) PDK2ACACAHPGDLMNASMN1; SMN2
SCHEMBL28388592 0.80 MAOA (0.44) HPGDLMNASMN1; SMN2KDM4EALDH1A1
SCHEMBL10153181 0.80 ACACA (0.43) PDK2ACACAHPGDLMNASMN1; SMN2
SCHEMBL10153955 0.80 ACACA (0.45) PDK2ACACAHPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed