SCHEMBL10153306

SCHEMBL10153306

COc1ccc(-c2c3ccccc3c(-c3c4ccccc4c(-c4ccc5c(c4)C(C)(C)c4ccccc4-5)c4ccccc34)c3ccccc23)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.41
IDO1 P14902 1/20 0.39
EP300 Q09472 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
IMPDH2 P12268 1/20 0.36
IMPDH1 P20839 1/20 0.36
ACACA Q13085 1/20 0.35
NQO1 P15559 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
MDM2 Q00987 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
DHODH Q02127 1/20 0.34
KDR P35968 1/20 0.33
PTPRC P08575 1/20 0.33
PTPN1 P18031 1/20 0.33
ALOX5 P09917 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153505 1.00 PDK2 (0.41) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL10153567 0.99 PDK2 (0.41) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL10153942 0.99 PDK2 (0.42) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL10153156 0.99 PDK2 (0.42) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL10153607 0.96 IDO1 (0.41) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL10153164 0.95 IDO1 (0.42) PDK2IDO1EP300KAT8L3MBTL1
SCHEMBL14600375 0.89 PDK2 (0.41) PDK2L3MBTL1ACACAKDM4EALDH1A1
SCHEMBL10153264 0.88 PDK2 (0.40) PDK2L3MBTL1ACACAKDM4EALDH1A1
SCHEMBL10153211 0.88 PDK2 (0.40) PDK2L3MBTL1ACACAKDM4EALDH1A1
SCHEMBL10153856 0.87 PDK2 (0.41) PDK2L3MBTL1ACACAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed