SCHEMBL10153607

SCHEMBL10153607

COc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3cc(-c5c6ccccc6c(-c6c7ccccc7c(-c7ccc(OC)c8ccccc78)c7ccccc67)c6ccccc56)ccc3-4)c3ccccc23)c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.41
EP300 Q09472 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
PDK2 Q15119 2/20 0.39
ACACA Q13085 1/20 0.37
NQO1 P15559 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
IMPDH2 P12268 1/20 0.36
IMPDH1 P20839 1/20 0.36
MAPT P10636 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
ALOX5 P09917 2/20 0.34
CHEK1 O14757 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
PRKD3 O94806 1/20 0.34
MAP4K4 O95819 1/20 0.34
PAK4 O96013 1/20 0.34
RET P07949 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153164 0.99 IDO1 (0.42) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153306 0.96 PDK2 (0.41) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153505 0.96 PDK2 (0.41) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153567 0.95 PDK2 (0.41) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153942 0.95 PDK2 (0.42) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153156 0.95 PDK2 (0.42) IDO1EP300KAT8PDK2ACACA
SCHEMBL10153900 0.88 KDM4E (0.40) PDK2ACACAL3MBTL1MAPTPDGFRA
SCHEMBL10153251 0.86 KDM4E (0.39) PDK2ACACAL3MBTL1MAPTPDGFRA
SCHEMBL10153491 0.86 KDM4E (0.41) PDK2ACACAL3MBTL1MAPTPDGFRA
SCHEMBL10153471 0.85 KDM4E (0.40) PDK2ACACAL3MBTL1MAPTPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed