Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763844 | 1.00 | CYP2C19 (0.62) | CYP2C19NR3C2HDAC1HDAC8HDAC6 | |
| SCHEMBL10269843 | 0.98 | CYP2C19 (0.59) | CYP2C19NR3C2HDAC1HDAC8HDAC6 | |
| SCHEMBL9446198 | 0.96 | CYP2C19 (0.68) | CYP2C19NR3C2HDAC1HDAC8HDAC6 | |
| SCHEMBL6834541 | 0.94 | CYP2C19 (0.70) | CYP2C19NR3C2HDAC1HDAC8HDAC6 | |
| SCHEMBL17735823 | 0.88 | CYP2C19 (0.63) | CYP2C19NR3C2CNR2CNR1TSHR | |
| SCHEMBL5918720 | 0.88 | CYP2C19 (0.63) | CYP2C19NR3C2CNR2CNR1TSHR | |
| SCHEMBL9215401 | 0.87 | HDAC1 (0.60) | CYP2C19NR3C2HDAC1HDAC8HDAC6 | |
| SCHEMBL17735825 | 0.86 | CYP2C19 (0.61) | CYP2C19NR3C2CNR2CNR1TSHR | |
| SCHEMBL13241961 | 0.86 | CYP2C19 (0.61) | CYP2C19NR3C2CNR2CNR1TSHR | |
| SCHEMBL18892831 | 0.85 | CYP2C19 (0.48) | CYP2C19CNR2CNR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120008068-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |