SCHEMBL9215401

SCHEMBL9215401

c1ccc(N(Cc2ccc(CN(c3ccccc3)c3ccccc3)cc2)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.60
HDAC8 Q9BY41 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
NR3C2 P08235 1/20 0.52
KCNA3 P22001 1/20 0.49
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 3/20 0.46
TAAR1 Q96RJ0 2/20 0.45
CNR2 P34972 1/20 0.43
AOC3 Q16853 1/20 0.42
KCNH2 Q12809 2/20 0.42
CYP2C19 P33261 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918512 0.94 NR3C2 (0.56) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL9215743 0.93 TAAR1 (0.56) HDAC1HDAC8HDAC6NR3C2KCNA3
Bromide SCHEMBL4613403 0.92 NR3C2 (0.55) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL9446230 0.92 NR3C2 (0.59) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL20859794 0.91 HDAC1 (0.53) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL20961703 0.91 HDAC1 (0.53) HDAC1HDAC8HDAC6NR3C2KCNA3
Ethylene SCHEMBL11428459 0.90 NR3C2 (0.53) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL23992546 0.89 TAAR1 (0.57) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL20881056 0.89 TP53 (0.54) HDAC1HDAC8HDAC6NR3C2KCNA3
SCHEMBL12260758 0.89 HDAC1 (0.56) HDAC1HDAC8HDAC6NR3C2KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170114237-A1 AQUEOUS INK FOR INKJET USE CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed
US-20170114237-A1 AQUEOUS INK FOR INKJET USE CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed
WO-2015152104-A1 AQUEOUS INK FOR INKJET USE CANON KABUSHIKI KAISHA (JP) 2015-10-08 WO disclosed
EP-1403325-B1 LIQUID CRYSTAL ORIENTATION AGENTS AND LIQUID CRYSTAL DISPLAY DEVICE WITH THE USE THEREOF NISSAN CHEMICAL IND LTD (JP) 2007-01-03 EP disclosed
EP-0517542-B1 Organic electroluminescence devices SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
EP-0517542-A1 Organic electroluminescence devices SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-12-09 EP disclosed