Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 5/20 | 0.34 |
| ▸ | CDK9 | P50750 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761390 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1461782 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL29134334 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| SCHEMBL6122857 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| SCHEMBL12466130 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| Hydrochloric Acid SCHEMBL28735985 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| Hydrochloric Acid SCHEMBL28735986 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| SCHEMBL24429365 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| SCHEMBL15384122 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1IRAK4CCNKCDK9 | |
| SCHEMBL13450092 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1IRAK4CCNKCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165309-A1 | HETERO RING DERIVATIVE | IL2, PIK3R2, IL2RA | KDM4E 3844/4885ALDH1A1 3496/4885IRAK4 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.