Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132478 | 0.74 | MAP2K4 (0.43) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL2132482 | 0.74 | MAP2K4 (0.43) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL3057752 | 0.71 | KDM4E (0.50) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL15485748 | 0.68 | KDM4E (0.47) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL4004747 | 0.68 | RAB9A (0.48) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL25270970 | 0.67 | KDM4E (0.46) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL24783278 | 0.67 | CYP1A2 (0.41) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL8206962 | 0.67 | KCNH2 (0.49) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL20805224 | 0.66 | DDB1 (0.58) | IDO1 | |
| SCHEMBL30273914 | 0.66 | DDB1 (0.58) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016117-A1 | INDAZOLEPROPIONIC ACID AMIDE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016117-A1 | INDAZOLEPROPIONIC ACID AMIDE COMPOUND | SCN9A, SCN1A, SCN1B | KDM4E 3922/4885GAA 4762/4885PDPK1 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.