SCHEMBL10155025

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156117	0.89	BACE1 (0.50)	BACE1ALDH1A1ALOX15LMNANPC1
	SCHEMBL10157798	0.81	BACE1 (0.53)	BACE1ALDH1A1LMNANPC1MEN1
	SCHEMBL10156206	0.80	AVPR1A (0.55)	BACE1ALDH1A1LMNATSHRMAPT
	SCHEMBL10156279	0.77	BACE1 (0.51)	BACE1ALDH1A1MEN1KMT2APKM
	SCHEMBL10156336	0.77	BACE1 (0.51)	BACE1ALDH1A1MEN1KMT2APKM
	SCHEMBL10154996	0.77	BACE1 (0.53)	BACE1ALDH1A1LMNAMEN1KMT2A
	SCHEMBL10157908	0.77	KDM4E (0.54)	BACE1ALDH1A1ALOX15MEN1KMT2A
	SCHEMBL10155498	0.76	BACE1 (0.55)	BACE1
	SCHEMBL10155525	0.75	BACE1 (0.56)	BACE1ALDH1A1
	SCHEMBL10157921	0.75	KMT2A (0.56)	BACE1ALDH1A1LMNANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.