SCHEMBL10157798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10156206	0.95	AVPR1A (0.55)	BACE1HPGDALDH1A1AVPR1AAVPR2
	SCHEMBL10155233	0.89	BACE1 (0.51)	BACE1RAB9ASMN1; SMN2HPGDKMT2A
	SCHEMBL10154702	0.84	TSHR (0.53)	BACE1SMN1; SMN2KMT2AALDH1A1AVPR1A
	SCHEMBL10154996	0.84	BACE1 (0.53)	BACE1SMN1; SMN2HPGDKMT2AALDH1A1
	SCHEMBL10155025	0.81	BACE1 (0.52)	BACE1RAB9ASMN1; SMN2NPC1KMT2A
	SCHEMBL10155525	0.78	BACE1 (0.56)	BACE1HPGDALDH1A1
	SCHEMBL10156336	0.78	BACE1 (0.51)	BACE1SMN1; SMN2KMT2AALDH1A1TSHR
	SCHEMBL10156279	0.78	BACE1 (0.51)	BACE1RAB9ASMN1; SMN2KMT2AALDH1A1
	SCHEMBL10157908	0.77	KDM4E (0.54)	BACE1SMN1; SMN2KMT2AALDH1A1TSHR
	SCHEMBL10155024	0.77	BACE1 (0.54)	BACE1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.