SCHEMBL10155476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10157698	0.90	BACE1 (0.52)	BACE1
	SCHEMBL10157658	0.90	BACE1 (0.60)	BACE1
	SCHEMBL14144056	0.88	BACE1 (0.51)	BACE1
	SCHEMBL10155947	0.87	BACE1 (0.50)	BACE1MAPTNAMPT
	SCHEMBL10155887	0.84	BACE1 (0.59)	BACE1MAPT
	SCHEMBL10156635	0.83	BACE1 (0.52)	BACE1NAMPT
	SCHEMBL10156593	0.83	SIRT1 (0.57)	TRPV1MAPT
	SCHEMBL10157518	0.82	BACE1 (0.54)	BACE1
	SCHEMBL14144328	0.82	BACE1 (0.54)	BACE1
	SCHEMBL10155154	0.82	NPC1 (0.55)	BACE1MAPTNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.