SCHEMBL10156308

SCHEMBL10156308

Cc1nc(CF)c(C)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6760698 0.77
SCHEMBL5543974 0.75
SCHEMBL16781846 0.75
SCHEMBL20498123 0.75
SCHEMBL10156309 0.75 GRM5 (0.34)
Hydrochloric Acid SCHEMBL5013629 0.73 SLC6A3 (0.38)
SCHEMBL10123483 0.73 SLC6A3 (0.38)
SCHEMBL20312853 0.73 CYP1A2 (0.31)
SCHEMBL5548739 0.71 SLC6A3 (0.37)
SCHEMBL2089836 0.71 SLC6A3 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120028970-A1 HETEROARYLTHIOMETHYL PYRIDINE DERIVATIVE MSD K.K. (JP) 2012-02-02 US disclosed
US-7732469-B2 for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi SYNGENTA CROP PROTECTION, INC. (US) 2010-06-08 US disclosed
US-20080227835-A1 Heterocyclic Amide Derivatives Useful as Microbiocides SYNGENTA CROP PROTECTION, INC. (US) 2008-09-18 US disclosed