Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.47 |
| ▸ | ITGAL | P20701 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060483 | 0.94 | ITGB2 (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL12749849 | 0.94 | ITGB2 (0.41) | ITGB2ICAM1ITGAL | |
| SCHEMBL10157533 | 0.92 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL12652125 | 0.91 | ITGB2 (0.45) | ITGB2ICAM1ITGAL | |
| SCHEMBL13185676 | 0.86 | ITGB2 (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL10156902 | 0.86 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL13185697 | 0.83 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL12060776 | 0.82 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL10155788 | 0.82 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL10156523 | 0.82 | ITGB2 (0.54) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035154-A1 | Modulators of Cellular Adhesion | SARcode Bioscience, Inc. (US) | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035154-A1 | Modulators of Cellular Adhesion | ITGB1, VCAM1, ITGB8 | ITGB2 8/4885ICAM1 5/4885ITGAL 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.