Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.88 |
| ▸ | DRD1 | P21728 | 1/20 | 0.88 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.88 |
| ▸ | PDE4A | P27815 | 1/20 | 0.88 |
| ▸ | SHH | Q15465 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.39 |
| ▸ | NECTIN4 | Q96NY8 | 5/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.38 |
| ▸ | MDM4 | O15151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415772 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL21250583 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8221832 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL14446856 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8415773 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8227154 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8420524 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8422213 | 1.00 | CTSL (0.88) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8420522 | 0.96 | CTSL (0.82) | CTSLDRD1PTGS1PDE4ASHH | |
| SCHEMBL8422141 | 0.96 | CTSL (0.92) | CTSLDRD1PTGS1PDE4ASHH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129342-B2 | High purity lipopeptides | CUBIST PHARMACEUTICALS, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-8058238-B2 | High purity lipopeptides | CUBIST PHARMACEUTICALS, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110207658-A1 | High Purity Lipopeptides | CUBIST PHARMACEUTICALS LLC (CH) | 2011-08-25 | — | — | US | disclosed |