Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | SHH | Q15465 | 1/20 | 0.58 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | SMO | Q99835 | 1/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386672 | 0.91 | ALB (0.64) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1015524 | 0.91 | ALB (0.58) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1017617 | 0.90 | ALB (0.55) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL15424139 | 0.89 | ALB (0.59) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1017518 | 0.89 | ALB (0.59) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1018176 | 0.89 | USP28 (0.68) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL30572237 | 0.89 | USP28 (0.68) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL17783734 | 0.88 | NPC1 (0.59) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1017948 | 0.87 | USP28 (0.55) | ALBHTR1ASLC6A2PDE4AOPRM1 | |
| SCHEMBL1251379 | 0.86 | ALB (0.54) | ALBHTR1ASLC6A2PDE4AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271642-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | Genentech, Inc. (US) | 2011-01-12 | — | — | EP | disclosed |