SCHEMBL10158486

SCHEMBL10158486

CO[Si](OC)(OC)c1ccc(F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.39
NFE2L2 Q16236 4/20 0.37
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
IDO1 P14902 3/20 0.34
TDO2 P48775 2/20 0.34
NQO2 P16083 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
GAA P10253 1/20 0.32
ABHD16A O95870 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15734775 0.93 NPC1 (0.40) ACHENPC1RAB9AIDO1TDO2
SCHEMBL50828 0.86 KDM4E (0.32) CA1CA2CA7CA9ALDH1A1
SCHEMBL15734337 0.83 CYP1A2 (0.33) ACHENFE2L2NPC1RAB9AGAA
SCHEMBL15734493 0.83 CYP1A2 (0.33) ACHENFE2L2NPC1RAB9AGAA
SCHEMBL15734831 0.83 NPSR1 (0.34) ACHENFE2L2NPC1RAB9AMAOA
SCHEMBL15738335 0.83 NPSR1 (0.34) ACHENFE2L2NPC1RAB9AMAOA
SCHEMBL15735022 0.78 NPC1 (0.34) NPC1RAB9AIDO1TDO2ALDH1A1
SCHEMBL15733811 0.78 NPC1 (0.34) NPC1RAB9AIDO1TDO2GAA
SCHEMBL15733585 0.78 NPC1 (0.37) NPC1RAB9AIDO1TDO2GAA
SCHEMBL15734438 0.78 ABCB1 (0.36) IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820740-B Engine cooling pipe and preparation process thereof 江阴标榜汽车部件股份有限公司 2024-05-10 CN claimed
CN-117820740-A Engine cooling pipe and preparation process thereof 江阴标榜汽车部件股份有限公司 2024-04-05 CN claimed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
CN-111298711-B Mesoporous Janus nanosheet emulsifier with pH responsiveness and preparation method and application thereof 湘潭大学 2021-09-24 CN claimed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN claimed
CN-111298711-A Mesoporous Janus nanosheet emulsifier with pH responsiveness and preparation method and application thereof 湘潭大学 2020-06-19 CN claimed
CN-117820740-B Engine cooling pipe and preparation process thereof 江阴标榜汽车部件股份有限公司 2024-05-10 CN disclosed
CN-117820740-A Engine cooling pipe and preparation process thereof 江阴标榜汽车部件股份有限公司 2024-04-05 CN disclosed
US-20230340266-A1 SILICON-CONTAINING COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE JSR CORPORATION (JP) 2023-10-26 US disclosed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN disclosed
CN-111298711-B Mesoporous Janus nanosheet emulsifier with pH responsiveness and preparation method and application thereof 湘潭大学 2021-09-24 CN disclosed
WO-2021122431-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO disclosed
EP-3838964-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS Covestro Deutschland AG (DE) 2021-06-23 EP disclosed
US-20150004791-A1 COMPOSITION FOR FORMING A COATING TYPE BPSG FILM, SUBSTRATE FORMED A FILM BY SAID COMPOSITION, AND PATTERNING PROCESS USING SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-01 US disclosed
US-20150004791-A1 COMPOSITION FOR FORMING A COATING TYPE BPSG FILM, SUBSTRATE FORMED A FILM BY SAID COMPOSITION, AND PATTERNING PROCESS USING SAID COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-01-01 US disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed
US-8501386-B2 Silicon-containing film-forming composition, silicon-containing film-formed substrate, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-08-06 US disclosed
US-20120052685-A1 SILICON-CONTAINING FILM-FORMING COMPOSITION, SILICON-CONTAINING FILM-FORMED SUBSTRATE, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-01 US disclosed