SCHEMBL50828

SCHEMBL50828

CO[Si](OC)(OC)c1ccc([Si](OC)(OC)OC)cc1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5404962 0.91
SCHEMBL3353844 0.91 ESR2 (0.33) MAPK1SMN1; SMN2
SCHEMBL13027864 0.88 NR1H2 (0.38)
SCHEMBL106097 0.88 ACHE (0.44) ALDH1A1CA1CA2CA7CA9
SCHEMBL14658322 0.88
SCHEMBL23521412 0.88
SCHEMBL5421380 0.88
SCHEMBL5420285 0.88
SCHEMBL1115633 0.86 CYP2A6 (0.42) ALDH1A1MAPK1
SCHEMBL21443909 0.86 ACHE (0.42) ALDH1A1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304819-A1 Flexible and foldable abrasion resistant photopatternable siloxane hard coat OPTITUNE OY (FI) 2025-10-02 US claimed
EP-4569015-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS Promega Corporation (US) 2025-06-18 EP claimed
WO-2025078379-A1 EASY TO CLEAN COATINGS WITH LOW FINGERPRINT VISIBILITY OPTITUNE OY (FI) 2025-04-17 WO claimed
CN-107636097-B Silicone polymer composition and use thereof 奥普提汀公司 2024-03-15 CN claimed
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION 2024-02-22 US claimed
WO-2024036277-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION (US) 2024-02-15 WO claimed
CN-117343638-A Porous spin-on dielectric coating materials from silicon-containing polymers 上海艾深斯科技有限公司 2024-01-05 CN claimed
US-11634610-B2 Siloxane polymer compositions and their use OPTITUNE OY (FI) 2023-04-25 US claimed
US-20220010172-A1 SILOXANE POLYMER COMPOSITIONS AND THEIR USE OPTITUNE OY (FI) 2022-01-13 US claimed
US-11127864-B2 Carbosiloxane polymer compositions, methods of producing the same and the use thereof OPTITUNE OY (FI) 2021-09-21 US claimed
US-7705062-B2 Nanoporous organosilicas as pre-concentration materials for sensors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-04-27 US claimed
US-20100099861-A1 SEPARATING AGENT FOR OPTICAL ISOMER NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-04-22 US claimed
US-20100038526-A1 Composition and method to characterize membranes' defects ENERGY MATERIALS CORPORATION 2010-02-18 US claimed
WO-2010019125-A1 COMPOSITION AND METHOD TO CHARACTERIZE MEMBRANES' DEFECTS ENERGY MATERIALS CORPORATION (US) 2010-02-18 WO claimed
EP-2145903-A1 SEPARATING AGENT FOR OPTICAL ISOMER National University Corporation Nagoya University (JP) 2010-01-20 EP claimed
US-20090075472-A1 METHODS TO MITIGATE PLASMA DAMAGE IN ORGANOSILICATE DIELECTRICS INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-03-19 US claimed
EP-1995214-A2 Multifunctional periodic mesoporous organosilica materials using block copolymer template and preparation method thereof Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-26 EP claimed
US-20080246153-A1 ORGANIC SILICA-BASED FILM, METHOD OF FORMING THE SAME, COMPOSITION FOR FORMING INSULATING FILM FOR SEMICONDUCTOR DEVICE, INTERCONNECT STRUCTURE, AND SEMICONDUCTOR DEVICE JSR CORPORATION (JP) 2008-10-09 US claimed
US-7399715-B2 Organic silica-based film, method of forming the same, composition for forming insulating film for semiconductor device, interconnect structure, and semiconductor device JSR CORPORATION (JP) 2008-07-15 US claimed
US-20070054418-A1 NANOPOROUS ORGANOSILICAS AS PRE-CONCENTRATION MATERIALS FOR SENSORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2007-03-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS COXFA4L2, LOXL1, LOX KDM4E 2443/4885ALDH1A1 912/4885MAPK1 2751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.