Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP7B1 | O75881 | 1/20 | 0.35 |
| ▸ | CYP7A1 | P22680 | 1/20 | 0.35 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269436 | 0.83 | AR (0.52) | CYP2C19CYP2C9ARCYP7B1CYP7A1 | |
| SCHEMBL19634237 | 0.83 | AR (0.52) | CYP2C19CYP2C9ARCYP7B1CYP7A1 | |
| SCHEMBL19625269 | 0.83 | AR (0.52) | CYP2C19CYP2C9ARCYP7B1CYP7A1 | |
| Stanozolol SCHEMBL6151066 | 0.82 | CYP2C19 (0.64) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| Stanozolol SCHEMBL44099 | 0.82 | CYP2C19 (0.64) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| Stanozolol SCHEMBL12417517 | 0.82 | CYP2C19 (0.64) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| Stanozolol SCHEMBL19645424 | 0.82 | CYP2C19 (0.64) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| SCHEMBL27046793 | 0.79 | CYP2C19 (0.52) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| SCHEMBL21392304 | 0.76 | CYP2C19 (0.49) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 | |
| SCHEMBL27046803 | 0.75 | CYP2C19 (0.45) | CYP2C19ADORA3ESR1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2446887-A2 | Use of danazol for the treatment of Alzheimer's disease | DMI Biosciences, Inc. (US) | 2012-05-02 | — | — | EP | disclosed |