SCHEMBL19634237

SCHEMBL19634237

CC12CCC3C(CCC4Cc5n[nH]cc5CC43C)C1CCC2O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.52
CYP19A1 P11511 3/20 0.51
GPBAR1 Q8TDU6 3/20 0.51
SHBG P04278 2/20 0.51
SERPINA6 P08185 2/20 0.51
CYP3A4 P08684 2/20 0.51
HSD17B10 Q99714 2/20 0.51
NR3C1 P04150 1/20 0.51
PGR P06401 1/20 0.51
NR3C2 P08235 1/20 0.51
MGAM O43451 1/20 0.51
CYP7B1 O75881 1/20 0.51
CYP7A1 P22680 1/20 0.51
PDK1 Q15118 2/20 0.49
PDK2 Q15119 2/20 0.49
PDK3 Q15120 2/20 0.49
PDK4 Q16654 2/20 0.49
LMNA P02545 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19625269 1.00 AR (0.52) ARCYP19A1GPBAR1SHBGSERPINA6
SCHEMBL10269436 1.00 AR (0.52) ARCYP19A1GPBAR1SHBGSERPINA6
Stanozolol SCHEMBL13724751 0.85 SHBG (0.61) ARCYP19A1GPBAR1SHBGSERPINA6
Stanozolol SCHEMBL6151066 0.83 CYP2C19 (0.64) ARSHBGCYP3A4HSD17B10NR3C1
Stanozolol SCHEMBL19645424 0.83 CYP2C19 (0.64) ARSHBGCYP3A4HSD17B10NR3C1
Stanozolol SCHEMBL44099 0.83 CYP2C19 (0.64) ARSHBGCYP3A4HSD17B10NR3C1
Stanozolol SCHEMBL12417517 0.83 CYP2C19 (0.64) ARSHBGCYP3A4HSD17B10NR3C1
SCHEMBL10158728 0.83 CYP2C19 (0.42) ARCYP3A4HSD17B10NR3C1PGR
SCHEMBL27046793 0.83 CYP2C19 (0.52) SHBGCYP3A4HSD17B10NR3C1PGR
SCHEMBL21392304 0.80 CYP2C19 (0.49) SHBGCYP3A4HSD17B10NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017201217-A1 DIHYDROTESTOSTERONE AND DIHYDROTESTOSTERONE DERIVATIVES AND PROMOTERS IN THE TREATMENT OF CANCER TYME, INC. (US) 2017-11-23 WO disclosed