Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25609423 | 0.79 | ATM (0.40) | ATMPOLB | |
| SCHEMBL13803799 | 0.75 | ATM (0.47) | ATMPOLB | |
| SCHEMBL2201585 | 0.75 | POLB (0.48) | ATMPOLB | |
| SCHEMBL14805854 | 0.73 | ATM (0.55) | ATMPOLB | |
| SCHEMBL18501700 | 0.73 | ATM (0.45) | ATMPOLB | |
| SCHEMBL25548564 | 0.71 | ATM (0.40) | ATM | |
| SCHEMBL20994692 | 0.70 | ATM (0.42) | ATMPOLB | |
| SCHEMBL15998913 | 0.70 | ATM (0.47) | ATMPOLB | |
| SCHEMBL17886878 | 0.70 | ATM (0.42) | ATMPOLB | |
| SCHEMBL24954636 | 0.69 | MAPT (0.49) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115819-A1 | Pentacycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115819-A1 | Pentacycline Compounds | TSLP, IL5, IL17A | ATM 4853/4885POLB 3931/4885PREP 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.