SCHEMBL101602

SCHEMBL101602

C=C(C)CCNc1ncnc2nc[nH]c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.67
CYP3A4 P08684 2/20 0.67
LMNA P02545 5/20 0.62
CYP1A2 P05177 4/20 0.60
CDK2 P24941 2/20 0.60
HIF1A Q16665 1/20 0.57
TSHR P16473 5/20 0.56
HSD17B10 Q99714 3/20 0.56
RECQL P46063 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC2 Q92769 1/20 0.56
MAPK1 P28482 2/20 0.56
TAAR1 Q96RJ0 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PRMT1 Q99873 2/20 0.52
TP53 P04637 2/20 0.52
ALDH1A1 P00352 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359033 1.00 HTT (0.67) HTTCYP3A4LMNACYP1A2CDK2
Hydrochloric Acid SCHEMBL30150738 0.99 HTT (0.65) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL28996851 0.86 CYP1A2 (0.55) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL7080798 0.83 HTT (0.47) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL546067 0.81 HTT (0.43) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL10345057 0.81 HDAC1 (0.67) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL29249244 0.81 CYP3A4 (0.45) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL7668701 0.80 CYP3A4 (1.00) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL9201457 0.80 HTT (1.00) HTTCYP3A4LMNACYP1A2CDK2
SCHEMBL30150726 0.80 CYP3A4 (0.44) HTTCYP3A4LMNACYP1A2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20392 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
EP-4659246-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES Atlas Data Storage, Inc. (US) 2025-12-10 EP claimed
US-20250368986-A1 ELECTROCHEMICAL SYNTHESIS WITH REDOX STABLE NUCLEOTIDES ATLAS DATA STORAGE INC (US) 2025-12-04 US claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 US claimed
WO-2025111452-A2 CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
WO-2004106508-A2 BIOREACTOR CONTAINING CELLS EXPRESSING GLYCOSYLTRANSFERASE NUCLEIC ACIDS THE UNIVERSITY OF YORK (GB) 2004-12-09 WO claimed
EP-1308511-A1 Use of angiopoietin-like 1 and angiopoietin-like 2 nucleic acids and proteins for the treatment of blood-related disorders and defects in vasculature. Mermaid Pharmaceuticals GmbH (DE) 2003-05-07 EP claimed
EP-1295130-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2003-03-26 EP claimed
JP-2002531470-A 2002-09-24 JP claimed
EP-1163374-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES Syntrix Biochip, Inc. (US) 2001-12-19 EP claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 WO claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 US claimed