Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 4/20 | 0.32 |
| ▸ | CES1 | P23141 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18386700 | 0.97 | TSHR (0.42) | LMNANFKB1TSHRPMP22CES2 | |
| SCHEMBL21467449 | 0.97 | TSHR (0.42) | LMNANFKB1TSHRPMP22CES2 | |
| SCHEMBL18862808 | 0.93 | SLC22A6 (0.39) | LMNANFKB1TSHRPMP22SLC22A6 | |
| SCHEMBL14383587 | 0.88 | LMNA (0.61) | LMNANFKB1TSHRPMP22SLC22A6 | |
| SCHEMBL21116024 | 0.88 | KMT2A (0.37) | LMNANFKB1TSHRPMP22CYP2D6 | |
| SCHEMBL14402220 | 0.88 | — | — | |
| SCHEMBL23516852 | 0.86 | — | — | |
| SCHEMBL9651246 | 0.86 | — | — | |
| SCHEMBL14302161 | 0.86 | PAOX (0.48) | LMNACES2CES1 | |
| SCHEMBL16256393 | 0.86 | TSHR (0.63) | LMNANFKB1TSHRPMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170306362-A1 | BIOCATALYTIC METHODS TO CONVERT CYCLOHEXANE OXIDATION PROCESS WASTE STREAMS TO USEFUL PRODUCTS | INVISTA NORTH AMERICA SARL (US) | 2017-10-26 | — | — | US | disclosed |
| EP-2606084-B1 | LIQUID COMPOSITION, RECORDING METHOD, AND RECORDED MATTER | RICOH CO LTD (JP) | 2017-10-25 | — | — | EP | disclosed |
| US-9334508-B2 | Methods of producing carboxylic acids | INVISTA NORTH AMERICA S.A.R.L. (US) | 2016-05-10 | — | — | US | disclosed |
| US-20130224807-A1 | METHODS OF PRODUCING CARBOXYLIC ACIDS | INVISTA NORTH AMERICA S.A R.L. (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2599814-A1 | COMPOUND, RADIATION-SENSITIVE COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN | Mitsubishi Gas Chemical Company, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-8241879-B2 | Biological methods for preparing adipic acid | VERDEZYNE, INC. (US) | 2012-08-14 | — | — | US | disclosed |
| US-20120021474-A1 | BIOLOGICAL METHODS FOR PREPARING ADIPIC ACID | VERDEZYNE, INC. (US) | 2012-01-26 | — | — | US | disclosed |