⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20852844 | 0.75 | — | — | |
| SCHEMBL8369697 | 0.73 | — | — | |
| SCHEMBL12597545 | 0.73 | — | — | |
| SCHEMBL11795810 | 0.73 | — | — | |
| SCHEMBL31096976 | 0.71 | — | — | |
| SCHEMBL141814 | 0.71 | — | — | |
| SCHEMBL18413728 | 0.71 | — | — | |
| SCHEMBL21712593 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL2190290 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL2240887 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492261-B1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | INFINITY DISCOVERY INC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-20130203724-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | INFINITY DISCOVERY, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| EP-1716119-B1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | INFINITY DISCOVERY INC (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2492261-A1 | Analogs of benzoquinone-containing ansamycins for the treatment of cancer | Infinity Discovery, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| US-8252779-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120108563-A1 | Methods Of Treating Liposarcoma | INFINITY PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| WO-2010135426-A1 | METHODS OF TREATING LIPOSARCOMA | INFINITY PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| US-7833997-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2010-11-16 | — | — | US | disclosed |
| US-7767662-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767663-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090088414-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | ADAMS JULIAN | 2009-04-02 | — | — | US | disclosed |
| US-20090088414-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | ADAMS JULIAN | 2009-04-02 | — | — | US | disclosed |
| US-20090069280-A1 | ANALOGS OF BENZOQUINONE-CONTAINING ANSAMYCINS AND METHODS OF USE THEREOF | ADAMS JULIAN | 2009-03-12 | — | — | US | disclosed |
| US-20090069280-A1 | ANALOGS OF BENZOQUINONE-CONTAINING ANSAMYCINS AND METHODS OF USE THEREOF | ADAMS JULIAN | 2009-03-12 | — | — | US | disclosed |
| US-20090062250-A1 | Analogs of Benzoquinone-Containing Ansamycins and Methods of Use Thereof | INFINITY PHARMACEUTICALS, INC. | 2009-03-05 | — | — | US | disclosed |
| US-7375217-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375217-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| US-7361647-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2008-04-22 | — | — | US | disclosed |
| US-7282493-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2007-10-16 | — | — | US | disclosed |
| US-7282493-B2 | Analogs of benzoquinone-containing ansamycins and methods of use thereof | INFINITY PHARMACEUTICALS, INC. (US) | 2007-10-16 | — | — | US | disclosed |